CYP3A43 and metastatic malignant neoplasm in the lymph nodes: Based on the above which we found that CYP3A43 underexpression was significantly associated with lymph node metastasis in LUAD patients, and stable CYP3A43 knockdown could enhance the proliferation of H1299 cells in vitro and in vivo; next, we determined the role of CYP3A43 in the migration ability of LUAD cells.