Based on the assumption that the EPHA2–ephrin-A1 interaction attenuates NSCLC growth and survival, Lee et al. used albumin mesosphere-conjugated ephrin-A1 in vivo, and suggested apoptosis induction, along with tumor shrinkage, in mouse NSCLC xenograft models [66]. The gene discussed is EPHA2; the disease is non-small cell lung carcinoma.