Recently, Yang et al. have ascertained a novel circRNA, circWSB1 (circ_0007716), which is highly expressed in breast cancer tissues, and can be activated by HIF-1α and impair the stability of the p53 protein by disturbing the interaction between p53 and ubiquitin-specific peptidase 10 (USP10) [68]. This evidence concerns the gene USP10 and breast carcinoma.