ABCB5 and vasculitis: Together, these observations suggest that endogenous ABCB5+ MSCs, in their physiological niche, mount an adaptive antioxidant response by SOD3 overexpression, to protect themselves from the threat of neutrophil oxidative burst, even though, at their low physiological numbers, they are not able to protect the skin from vasculitis and vasculitis-associated tissue breakdown [88].