DSCAM and Down syndrome: Supplementary Table S26 (data from [86]) lists 14 epigenomic change annotations for in Downs Syndrome Cell Adhesion Molecule (DSCAM) and in its closely related homologue DSCAM-Like 1 (DSCAML1), proteins which have previously been implicated in central and peripheral nervous system development and involved in neurite guidance and self-avoidance in the brain and retina, and axonal crossing of the midline in the spinal cord [109].