Moreover, there were annotations in the epigenomic study by Schrott and colleagues [86] describing two hits for ALDH1A1 one each in dependence and withdrawal with Bonferroni-adjusted p-values of 0.0106 and 0.0291, and nine other hits for members of the ALDH1 family in cannabis dependence and withdrawal. The gene discussed is ALDH1A1; the disease is cannabis dependence.