Considering the overall PCa patients, in Ashkenazi patients we identified a total of 46 (40.4%) germline BRCA1 (3,490 PCas) and 68 (59.6%) BRCA2 (3,527 PCas) variants, and in non-Ashkenazi patients 108 (21.2%) BRCA1 (23,767 PCas) and 402 (78.8%) BRCA2 (21,106 PCas) variants. Here, BRCA1 is linked to posterior cortical atrophy.