There are several genes associated with hereditary PCa, with variable frequencies: HOXB13 (0.6–6.25%), BRCA2 (1.2–5.3%), CHEK2 (1.6–2.7%), ATM (1.6–2.7%), MMR (0.7–1.74%), BRCA1 (0.9–1.25%), PALB2 (0.4- 0.5%), BRP1, and NBS1 (0.1–0.2%) [51,52,53]. The gene discussed is MRC1; the disease is posterior cortical atrophy.