VEGFA and vascular neoplasm: Because NETs are highly vascular tumors and express vascular endothelial growth factor (VEGF), multi-tyrosine kinase receptor inhibitors including those that target VEGF, platelet-derived growth factor receptors (PDGFRs), and Fibroblast growth factor receptors (FGFRs), have been studied extensively in metastatic GEP-NETs [132,133,134].