The results of the study suggested that Gen pre-exposed rats showed decreased expression of matrix metalloproteinase-3 (MMP3), rho associated coiled-coil containing protein kinase 2 (ROCK2), VGF nerve growth factor inducible, and Alpha-1 antitrypsin (SERPINA1), whose overexpression has previously been associated with carcinogenesis in various types of human cancers. Here, SERPINA1 is linked to cancer.