Among the examined models, we discovered a statistically significant diagnostic model consisting of hepcidin and IL-6 in the differential diagnosis of females without anaemia from females who will develop anaemia post-operatively during the hospitalization, with the highest sensitivity (87.5%) and specificity (71.4%), as well as an area under the curve (AUC) value considered excellent (0.8809). Here, IL6 is linked to anemia (phenotype).