So, here we introduce AnxA2, as a Ca2+-dependent phospholipid-binding protein, and an AnxA2 mRNA-binding protein [33] which has been implicated in many cancers like breast, prostate, ovarian, etc., as it helps cancer cells to migrate, invade, and proliferate in the tumor microenvironment [34]. The gene discussed is ANXA2; the disease is neoplasm.