A list of common network signatures shared between LC and HCC patients center on the gut virus Stenotrophomonas virus DLP5 and uncultured Caudovirales phage, the plasma metabolites pyruvic acid and acetic acid, and the plasma cytokines/chemokines eotaxin and PDGF-AB/BB, regardless of etiology. The gene discussed is CCL11; the disease is hepatocellular carcinoma.