According to our study on pMMR metastatic CRC patients, there is a significant favourable prognostic effect of tumour cell PD-L1 expression in the pulmonary metastases and a suggestive favourable prognostic effect of PD-1 expression in the invasive margin and tumour centre of pulmonary metastases; the immune cell PD-L1 values showed no survival effect. This evidence concerns the gene PDCD1 and colorectal carcinoma.