SOCE plays essential functional roles in breast cancer cell biology and the development of different breast cancer hallmarks, including cell viability and survival, migration, proliferation and apoptosis resistance [36,52,53,54]; however, the possible cellular effects of Orai1 and STIM1 N-linked glycosylation in breast epithelial and breast cancer cells remains unknown. The gene discussed is ORAI1; the disease is breast cancer.