S100A10 and lung adenocarcinoma: In lung squamous cell carcinoma, the expression of S100A10 in tumor tissue was positively correlated with tumor size, TMN stage, and lymphatic metastasis [8], while elevated S100A10 in lung adenocarcinoma indicated poorer tumor differentiation, higher TMN stage, more frequent intratumoral vascular invasion and a poorer prognosis [17].