Particularly, the presence of the (CK+/JUNB+/CXCR4+) phenotype in NSCLC patients was linked to poorer PFS (Kaplan–Meier, Log Rank, p = 0.007, HR = 5.21, Cox regression: p = 0.017, HR = 1.66) and OS (Cox regression: p = 0.011, HR = 2.16). This evidence concerns the gene JUNB and non-small cell lung carcinoma.