For example, in colorectal cancer tissue, CXCL1, CXCL2, CXCL3, CXCL5, CXCL8, and CXCL11 were highly expressed, while CXCL12, CXCL13, and CXCL14 were little expressed [133]. The gene discussed is CXCL12; the disease is colorectal cancer.