ICAM1 and cervical cancer: Indeed, in human breast, prostate, liver, lung, and cervix cancer cells, this compound caused apoptosis, suppressing invasion and metastasis through enhancing DNA fragmentation, suppressing interleukins levels (IL-6 and IL-8), increasing caspase-3 and -8 activity, decreasing matrix metalloproteinases (MMP), intercellular adhesion molecule 1 (ICAM-1) level, vascular endothelial growth factor (VEGF) level, and Na+-K+-ATPase activity [38].