Immunization with citrullinated [34,37,77] Vim and ENO1 peptides increase survival of HLA-DR4 transgenic mice implanted with B16F1 tumors expressing HLA-DR4, as well as Lewis lung carcinoma cells (LLC/2), ovarian cancer cells (ID8), and pancreatic cancer cells (Pan02) [17]. This evidence concerns the gene ENO1 and pancreatic neoplasm.