Additionally, the results of the Western blot indicated that the protein expression of BCL-2, N-cadherin, and vimentin was upregulated, whereas Cleaved-caspase 3, Cleaved-caspase 9, and E-cadherin expression was downregulated in RCC cells treated with exosomes (Figure 3F,G). The gene discussed is CDH2; the disease is renal cell carcinoma.