CD33 and acute myeloid leukemia: To improve the proliferation and cytotoxic activity of CD33-targeting CAR-NK cells, Albinger et al. [78] demonstrated the possibility of transducing blood-derived primary NK cells with CAR-encoding pseudotyped baboon envelope lentiviral vectors (BaEV-LVs), leading to stable CAR expression in NK cells and their great anti-tumor potency in mouse models of AML [78].