Inhibition of LDHA by genic tools or pharmacological reagents has been reported to induce oxidative stress [137,138,139], decrease cellular proliferation [140], promote cell death [138], activate apoptosis [139,141], enhance tumor suppressor p53 expression [17], suppress the inflammatory response [129], and restore the immune functions [129,142] in a variety of cancer cell lines. The gene discussed is LDHA; the disease is cancer.