LDHD and cancer: Up to date, the lactate oxidative metabolism in the prostate mitochondria is based on the putative LDH located at the mitochondrial inner (an mLDH for L-lactate metabolism [91,105] and D-lactate dehydrogenase (LDHD) for D-lactate metabolism [53,106,107]); whether the phenomena occur in other cancers remains to be verified.