PRKN and neoplasm: The detailed expression pattern of mitophagy genes were listed in Figure 5B. To be noted, there were 10 genes upregulated in high risk mitophagy group and in tumor tissues (CSKN2A1, CSKN2B, MFN1, MTERF3, PGAM5, RPS27A, TOMM22, TOMM40, TOMM5 and VDAC1, Figure 1A,B and Figure 5B) and 4 genes downregulated in high risk mitophagy group and the tumor tissues (MAP1LC3A, MAP1LC3B, PINK1 and PRKN, Figure 1A,B and Figure 5B).