Fatigue (n = 14), anorexia (n = 8), increased alanine aminotransferase (ALT) (n = 7) or aspartate aminotransferase (AST) (n = 7), rash (n = 6), hypertension (n = 5), and hoarseness (n = 5), were the most common TRAEs of any grade. This evidence concerns the gene GPT and Hypertension.