Inflammatory markers, including IL-6, IL-8, TNF-α, TGF-β1, CRP, and ferritin have been involved in the recruitment of neutrophils and initiation of hepatocellular inflammation, and also associated with hepatic fibrosis liver as well as damage and progression to NASH [77,154]. The gene discussed is TGFB1; the disease is metabolic dysfunction-associated steatohepatitis.