Increased expression of GLUT1 is observed not only in HCC [38] but also in CCA, where it correlates with poor tumor differentiation grade and with a significantly shorter overall survival of patients [39,40]; PDK1, PDK2 and PDK3 were also found to be significantly overexpressed in CCA tissues [41]. The gene discussed is SLC2A1; the disease is hepatocellular carcinoma.