Moreover, Abdelsadek et al., in their discussion, commented on the study of Kheyamis, which demonstrated that the expression of vitamin D receptors (VDR) was increased in diabetic neuropathy patients, and this upregulation of VDR was associated with the severity of neuropathy and peroneal nerve conduction velocity, with no difference in VDR expression being observed between painless neuropathy and painful neuropathy [16]. This evidence concerns the gene VDR and neuropathy.