Houssier et al. suggested that CD36 deficiency downregulates retinal POS-induced proangiogenic cyclooxygenase (COX)-2 and vascular endothelial growth factor (VEGF) expression, resulting in choroidal capillary rarefacialization and photoreceptor and choroidal degeneration, leading to dry AMD [66]. The gene discussed is VEGFA; the disease is dry age related macular degeneration.