THBS1 and age-related macular degeneration: At present, the studies on the role of CD36 in the occurrence and development of eye diseases mainly focus on AMD, DR, etc., and it has been found that TSP-1, EP80317, MPE-001, and other proteins or derivative ligands can interact with CD36 to inhibit the pathological processes such as abnormal lipid metabolism, oxidative stress damage, or vascular abnormalities through intracellular signal transduction.