Additionally, in 2014, Yao et al. reported that the overexpression of PPARβ/δ prevented the proliferation of breast cancer cells, MDA-MB-231 and MCF7, while the treatment of the agonist GW0742 further inhibited the proliferation of MCF7 cells without any effect on the MDA-MB-231 cells. The gene discussed is PPARD; the disease is breast cancer.