PPARG and neoplasm: In addition to the above effects, a large number of reports also pointed out that ligand-activated PPARγ exerts anti-tumor effects by promoting cell apoptosis and preventing cell proliferation, regulating cell metastasis, and stimulating angiogenesis, thereby inhibiting the occurrence and development of tumors of the liver [173], bladder [174], lung [175,176], brain [177], thyroid [178], esophagus [179] and colorectum [180,181,182,183].