In contrast, 15-PGDH gene expression was significantly decreased by about five-fold (8.2 × 10−5 ± 3.75 × 10−5, p < 0.05) versus (3.9 × 10−4 ± 1.69 × 10−4) in response to ONNV MOI 1 infection at 24 h (Figure 8d). This evidence concerns the gene HPGD and infection.