SLC2A2 and glycogen storage disease due to GLUT2 deficiency: Confirmation of the significance of GLUT2 in glucose reabsorption was elucidated in murine and human studies showing that the functional loss of GLUT2, either by a genetic knockout of the SLC2A2 gene in vivo or mutations in humans [Fanconi- Bickel Syndrome (FBS)], led to glucosuria [20,26,27] (see Section 3).