TNFRSF4 and malignant colon neoplasm: Mouse CT26 colon cancer tumors are not infected by SV yet are successfully treated with SV.IL-12 and OX40 antibody administered one time per week for 4 weeks, whereas MyC-CaP prostate tumors, which are susceptible to SV infection, require four injections per week for 4 weeks to eliminate tumor growth [7].