In PD, these correlations were generally weakened (Supplementary Figures S7j–l,n and S8j–l, S8n for OPA1 and VAPB, respectively), except in putamen, where the negative correlations were slightly enhanced (Supplementary Figures S7m and S8m for OPA1 and VAPB, respectively). This evidence concerns the gene OPA1 and Parkinson disease.