Based on our results, we can observe that at least two molecules related to the activity of the inflammasome (LDH and caspase-1, Table 3) and a cytokine product of its activity (IL-18, Table 3 and Figure 1), in addition to a cytokine pro-inflammatory (INF-γ, Table 3) were higher in patients with ILD associated with ASSD. The gene discussed is CASP1; the disease is interstitial lung disease.