CD4 and neoplasm: Morphometric analysis (Figure 3C,D) indicated the significant increase of CD4+ and CD8+ lymphocytes density in the tumor side GBM (CD4+: 2.4 ± 0.33%, CD8+: 0.24 ± 0.04%), as compared to the CTRL (CD4+: 0.4 ± 0.02%; CD8+: 0.02 ± 0.001%).