PTPRJ was identified as a direct target of miR-155 in colorectal cancer, and the ectopic expression of PTPRJ was found to inhibit cell growth, migration, and invasiveness in the colorectal cancer cell line HCT116, revealing a key role for the miR-155/PTPRJ/AKT axis in cell proliferation and migration [23]. This evidence concerns the gene AKT1 and colorectal cancer.