It was shown that targets of the drug combinations (including TNF, IL1B, IL10, and CCL2) (p=5.72×10−5) and, specifically, its individual drugs including EH (p = 0.00142), PR (p=4.37×10−4), and GR (p=5.81×10−5) are significantly overlapped with COVID-19-related genes obtained from the CTD database. This evidence concerns the gene TNF and COVID-19.