TLR polymorphism with a significant association with pulmonary tuberculosis was present in TLR1 rs5743572 in intron, TLR2 rs3804100 in exon, and TLR6 rs5743808 in exon and among MDR-TB isolates from patients with pulmonary MDR-TB of a severe and moderate/mild degree [45]. The gene discussed is TLR1; the disease is pulmonary tuberculosis.