Phenotypic variation exists among individuals with SHOX deficiency because a high-arched palate is more prevalent in Turner syndrome, whereas Madelung deformity, a short forearm and lower leg, bowing of the forearm and tibia, and muscular hypertrophy are more prevalent in Léri–Weill syndrome [17]. This evidence concerns the gene SHOX and hyperinsulinemic hypoglycemia, familial, 4.