Not only this, but there have also been described ccRCCs with a hybrid combination of borderline morphological patterns, namely gland/nest-like and papillary and immunomarkers such as negative or focal/>50% of neoplastic cells with CK7 positivity, typical in ccpRCC, and CD10 and CAIX positivity, but peculiar in ccRCC [19]. This evidence concerns the gene CA9 and nonpapillary renal cell carcinoma.