Recently, Sethi et al., using laser microdissection of the glomeruli and mass spectrometry, have identified new antigens in the glomeruli of patients with MN negative for anti-PLA2R and anti-THSD7A, such as exostosin 1 and 2 in the glomeruli of patients with MN secondary to autoimmune diseases, especially SLE; NELL-1 (neural epidermal growth factor-like 1 protein) in a cohort of MN patients [16,17]; semaphorin 3B (Sema 3B), another uncommon antigen that is more prevalent in the pediatric population; and protocadherin 7 (PCDH7), whose role in MN is yet to be determined. Here, NELL1 is linked to systemic lupus erythematosus.