Cheng et al. [41] reported that the predictive performance of CU-HCC, PAGE-B, modified PAGE-B, and their suggested HCC-nomogram using albumin-bilirubin score at 1-year of AVT in 277 treatment-naïve patients with HBV cirrhosis was very limited (0.505–0.611). This evidence concerns the gene ALB and hepatocellular carcinoma.