The expression of 17 SFs (HNRNPD, HNRNPH3, SRSF8, HNRNPU, SRSF5, SRSF2, HNRNPDL, HNRNPAB, SRSF7, HNRNPA1, SRSF1, HNRNPR, SRSF6, SRSF11, HNRNPH1, SRSF10, SRSF12) was up-regulated in AML samples. The gene discussed is SRSF1; the disease is acute myeloid leukemia.