Of the patient who underwent cytology (10 patients in IPMN-LGD and 17 patients in Ad-IPMN), three patients in LGD-IPMN and five patients in Ad-IPMN were evaluated for KRAS mutation, and two patients in LGD-IPMN and four patients in Ad-IPMN presented a mutation of KRAS status. Here, KRAS is linked to pancreatic intraductal papillary-mucinous neoplasm.