In addition, since it has been confirmed that the HR of metabolic PLC burden (HR = 4.5373) using FDG PET/CT is greater than that of cPLC (HR between cPLC1 and cPLC3 = 4.0577) known through only CT, FDG PET with CT may be considered useful imaging modality in evaluating the overall tumor burden of PLC. This evidence concerns the gene HSPG2 and neoplasm.