(p = 0.62,) The 3 bp deletion, rs66650371 HBS1L-MYB variant allele (–/TAC and −/−) was found to be significantly associated with HbF level in SCA patient (p:0.02, The polymorphism in the Gγ globin promoter region; Xmn1 polymorphism residing in −158 (C → T) (HBG2 c.-211C → T) was screened in patients. The gene discussed is HBG2; the disease is autosomal dominant cerebellar ataxia.