Since CD98 is crucial for the correct intake of essential amino acids, which are an important part of cellular homeostasis [32], we asked whether CD98hc depletion could also lead to the disappearance/death of some of the original 8 type II NBs (per lobe), this way reducing the number of cells capable of originating the tumor and, thus, indirectly preventing tumor formation. The gene discussed is SLC3A2; the disease is neoplasm.