To expand our study of DEGs in murine CLL-like cells and their surrounding tumor microenvironment, unselected live cells from spleens of Eμ-PRMT5 and Eμ-TCL1 mice at ERC (Supplemental Fig. 2B) were processed for 3’ scRNA-seq. The gene discussed is PRMT5; the disease is B-cell chronic lymphocytic leukemia.