PRMT5 and B-cell chronic lymphocytic leukemia: In concordance with the observed frequency of CLL-like development in Eμ-PRMT5 mice, aberrant PRMT5 expression as the sole transgenic event appeared as a less-robust murine leukemogenic driver as a greater degree of clonal diversity was observed in Eμ-PRMT5 mice when directly compared to the B-cell compartment of Eμ-TCL1 mice.