The most changed components of BM included laminins (LAMB2, LAMA2, LAMC3, LAMB1, LAMC1, and LAMA5) and proteoglycans (COL18A1, HSPG2, and AGRN), with some BM specific collagens (IV, VIII, XVIII, and V collagens) remaining in COVID-19 brains, as compared with the control brains (Fig. 2f). The gene discussed is LAMC3; the disease is COVID-19.