Briefly considering common disease themes between Alzheimer’s disease and the ALS-Ox subtype, expression of oxidation-associated transcripts COX4I2, NDUFA4L2, and OXR1 is consistent with reported literature68–70, although CP is known to be upregulated in Alzheimer’s55 (Fig. 6). This evidence concerns the gene COX4I2 and amyotrophic lateral sclerosis.