Moreover, the level of TANs infiltration was significantly correlated with the expression of apoptotic genes, including TNFRSF10C and TNFRSF10D, and with expression of the neutrophil marker genes CXCR1, S100A9. In order to investigate the effect of peripheral blood neutrophils on the prognosis of GBM (CNS5), data from 143 patients was analyzed. The gene discussed is CXCR1; the disease is glioblastoma.